Lung function in the total cohort and by IPF disease duration

ParameterPatients nTotal cohortSubgroups
Prevalent IPF#Incident IPFp-value
Patients n502331171
Total lung capacity L4694.4±1.44.4±1.54.6±1.20.228
Total lung capacity % pred46970.2±21.169.4±24.071.8±14.30.378
Inspiratory vital capacity L4402.6±0.92.6±0.92.7±0.80.638
Inspiratory vital capacity % pred44072.2±20.071.9±20.472.8±19.30.584
FVC L4472.6±0.82.5±0.92.6±0.80.584
FVC % pred44772.2±20.671.7±19.773.7±19.30.346
FEV1 L4852.2±0.72.2±0.72.2±0.60.334
FEV1 % pred48574.7±19.873.5±20.276.9±18.70.068
FEV1/FVC % pred447112.3±11.9111.6±11.8113.6±12.10.098
DLCO mL·min−1·mmHg−140810.4±4.910.2±4.411.0±5.60.089
DLCO % pred40835.5±15.534.4±14.137.7±17.60.041
PAO2 mmHg46167.8±11.767.2±12.468.9±10.20.158
PACO2 % pred46138.9±6.239.5±6.837.6±4.40.001
  • Data are presented as n or mean±sd. FVC: forced vital capacity; FEV1: forced expiratory volume in 1 s; DLCO: diffusing capacity of the lung for carbon monoxide; PAO2: alveolar oxygen tension; PACO2: alveolar carbon dioxide tension. #: duration since diagnosis ≥6 months; : duration since diagnosis <6 months.