Parameter | Patients n | Total cohort | Subgroups | ||
Prevalent IPF# | Incident IPF¶ | p-value | |||
Patients n | 502 | 331 | 171 | ||
Total lung capacity L | 469 | 4.4±1.4 | 4.4±1.5 | 4.6±1.2 | 0.228 |
Total lung capacity % pred | 469 | 70.2±21.1 | 69.4±24.0 | 71.8±14.3 | 0.378 |
Inspiratory vital capacity L | 440 | 2.6±0.9 | 2.6±0.9 | 2.7±0.8 | 0.638 |
Inspiratory vital capacity % pred | 440 | 72.2±20.0 | 71.9±20.4 | 72.8±19.3 | 0.584 |
FVC L | 447 | 2.6±0.8 | 2.5±0.9 | 2.6±0.8 | 0.584 |
FVC % pred | 447 | 72.2±20.6 | 71.7±19.7 | 73.7±19.3 | 0.346 |
FEV1 L | 485 | 2.2±0.7 | 2.2±0.7 | 2.2±0.6 | 0.334 |
FEV1 % pred | 485 | 74.7±19.8 | 73.5±20.2 | 76.9±18.7 | 0.068 |
FEV1/FVC | 447 | 0.9±0.1 | 0.9±0.1 | 0.9±0.1 | 0.361 |
FEV1/FVC % pred | 447 | 112.3±11.9 | 111.6±11.8 | 113.6±12.1 | 0.098 |
DLCO mL·min−1·mmHg−1 | 408 | 10.4±4.9 | 10.2±4.4 | 11.0±5.6 | 0.089 |
DLCO % pred | 408 | 35.5±15.5 | 34.4±14.1 | 37.7±17.6 | 0.041 |
PAO2 mmHg | 461 | 67.8±11.7 | 67.2±12.4 | 68.9±10.2 | 0.158 |
PACO2 % pred | 461 | 38.9±6.2 | 39.5±6.8 | 37.6±4.4 | 0.001 |
Data are presented as n or mean±sd. FVC: forced vital capacity; FEV1: forced expiratory volume in 1 s; DLCO: diffusing capacity of the lung for carbon monoxide; PAO2: alveolar oxygen tension; PACO2: alveolar carbon dioxide tension. #: duration since diagnosis ≥6 months; ¶: duration since diagnosis <6 months.