Infectious respiratory events: clinical, radiological and biological characteristics and treatments
| Invasive fungal infection | Bacterial pneumonia | |
| Events n | 30 | 30 |
| Anti-infectious prophylaxis | Itraconazole | TMP-SMX |
| Prescriptions | 24/29 | 26/27 |
| Clinical signs at diagnosis n/N (%) | ||
| Fever | 13/27 (48) | 17/27 (63) |
| Respiratory function signs# | 13/27 (48) | 17/27 (63) |
| Fever or respiratory function signs# | 17/27 (63) | 24/27 (89) |
| Chest pain | 5/27 (18.5) | 6/27 (22) |
| Respiratory failure | 2/27 | 3/27 |
| Biology | ||
| PMNs ×109 cells·L−1 | 6.0±3.5 | 6.7±3 |
| CRP mg·L−1 | 68±85 | 106±90 |
| Platelets ×109 cells·L−1 | 297±117 | 302±125 |
| Radiological features at diagnosis n | 23 | 13 |
| Nodule n | 12 | 6 |
| Alveolar consolidation n | 20 | 10 |
| Ground-glass opacities n | 11 | 5 |
| Reticulations n | 10 | 2 |
| Bronchiectasis n | 4 | 2 |
| Radiological scarring after treatment | 9/9 | 3/7 |
| Bronchoalveolar lavage n | 19 | 7 |
| Cells ×103 cells·mL−1 | 675±1187 | 419±372 |
| Macrophages % | 43 | 38 |
| Neutrophils % | 23 | 21 |
| Lymphocytes % | 36 | 38 |
| Eosinophils % | 7 | 6 |
| Pulmonary biopsy | 10/30 | 4/30 |
| Treatment | ||
| Lines of treatment n mean | 2.2 | 1.7 |
| Associated treatments n | 11 | 4 |
| Interferon-γ n | 7 | 1 |
| Granulocyte transfusion n | 5 | 1 |
| Surgery n | 0 | 2 |
| Immunomodulator n | 6 | 0 |
Data are presented as n/N or mean±sd, unless otherwise stated. TMP-SMX: trimethoprim-sulfamethoxazole; PMN: polymorphonuclear neutrophil; CRP: C-reactive protein. #: dyspnoea, cough or purulent sputum.