TABLE 1 Policy and implementation data on Xpert MTB/RIF from 22 high tuberculosis (TB) burden countries
Country (WHO classification)Estimated HIV+ TB cases# nEstimated MDR-TB among notified TB cases# nTotal MDR cases that are new TB cases#,¶ %Xpert policyCartridges procured§ nSmear/Xpert cartridge ratioƒModules procured§ nAvailability in private sectorAlgorithmSLT initiation
Patients with high risk of DRPatients with low risk of DR
Afghanistan310115065N570 (460)37.06NDRTreat w/DSTTreat w/ DST
Bangladesh (HDR)240420045Y114 910 (96 300)15.0376Y w/PPMDRTreat no DSTTreat w/ DST
Brazil
(HTH)
16 000171050Y290 930 (256 670)6.2716Y w/o PPMAll
EPTB
Children
Under revision
Cambodia
(HTH)
270038685Y57 640 (20 690)21.196NDR
HIV+
Treat w/DSTWait
China
(HDR, HTH)
730060 00082Y240 000 (227 560)74.33812Y w/o PPMDRTreat no DSTWait
DR Congo
(HDR, HTH)
16 000286073Y67 740 (24 780)31.2110NDR
HIV+
Treat w/DSTTreat w/DST
Ethiopia
(HDR, HTH)
23 000208077Y37 040 (12 680)378.5104Y w/o PPMDR
HIV+
Children
Treat no DSTTreat w/o DST
India
(HDR, HTH)
130 00064 00033Y379 200 (232 150)71.5598Y w/PPMDR
HIV+
Children
Treat w/DSTWait
Indonesia
(HDR, HTH)
7500680085Y52 950 (41 250)39.3284Y w/PPMDR
HIV+
Treat w/DSTWait
Kenya
(HTH)
45 000278065Y147 950 (81 010)47.6370Y w/PPMDR
HIV+
Children
Treat w/DSTWait
Mozambique
(HTH)
83 000194072Y76 020 (31 700)6.2108NDR
HIV+
Children
Treat w/DSTTreat w/DST
Myanmar
(HDR, HTH)
19 000610080Y72 520 (40 100)23.2164NDR
HIV+
Children
WaitWait
Nigeria
(HDR, HTH)
46 000360069Y76 840 (38 080)27.8400Y w/PPMDR
HIV+
EPTB
WaitWait
Pakistan
(HDR)
380011 40068Y98 200 (45 860)31.0294Y w/PPMDR
HIV+
EPTB
Treat w/DSTWait for 2nd Xpert
Philippines
(HDR)
46015 30055Y71 780 (34 350)41.9404Y w/PPMDR
HIV+
EPTB
Children
WaitWait
Russia (HDR, HTH)930045 00044N15 490 (2 950)2386.458NAllTreat w/DSTTreat w/DST
South Africa
(HDR, HTH)
330 000810043Y4 228 480 (2 312 280)1.64132Y w/o PPMALL
EPTB
Children
Treat w/DSTWait
Tanzania32 000500100Y113 550 (56 640)12.0192NDR,
Unknown HIV+
Children
Treat w/o DSTWait
Thailand
(HTH)
12 000176045Y24 560 (10 330)123.985Y w/o PPMDR
HIV+ (smear)
Treat w/DSTWait
Uganda
(HTH)
35 000101053Y84 560 (50 340)4.1266NDR
HIV+ (smear)
Treat w/ or w/o DST##Wait
Vietnam
(HDR, HTH)
9300380055Y54 930 (31 130)62.6158Y w/o PPMDR
HIV+
Children
Treat w/DSTWait
Zimbabwe
(HTH)
55 00093061Y146 340 (83 590)0.6300NDR
Unknown HIV+
Children
Under revision
  • WHO: World Health Organization; MDR: multidrug-resistant; SLT: second-line treatment; DR: drug resistance; HDR: high MDR-TB burden; HTH: high TB/HIV burden; N: no; Y: yes; PPM: private–public mix initiatives (initiatives encouraged by WHO to promote the collaboration between private and public health providers in the delivery of TB care); EPTB: extrapulmonary TB HIV+ (smear): HIV+ patients presumed to have TB but with a negative smear; DST: drug susceptibility testing; wait: do not start until DR is confirmed. #: in 2012 [1]. : rather than retreatment TB patients. §: accumulated procurement until June 30, 2014 (and the accumulated procurement in the past 12 months) [4], under concessional pricing; the data do not include private sector procurement. ƒ: ratio of the numbers of smears performed in high-burden countries for initial diagnosis to the numbers of Xpert cartridges procured in the same country; the annual smear volumes were collected for the year 2012 [5], the numbers of Xpert cartridges procured were for the last 12 months (July 2013 to June 2014). ##: in Uganda, DR-TB contacts with TB symptoms require no confirmation before initiating SLT (w/o DST), while the other Xpert RIF-resistant patients suspected to have DR-TB will start on SLT with confirmatory DST.