OR | 95% CI | p-value | C-index | Sensitivity, % (95% CI) | Specificity, % (95% CI) | PPV, % (95% CI) | NPV, % (95% CI) | |
sPESI ≥1 | 8.38 | 1.96–35.85 | 0.004 | 0.67 | 92 (75–98) | 42 (38–46) | 6 (4–8) | 99 (97–100) |
Additional impact of the age-adjusted hsTnT cut-off value | ||||||||
sPESI ≥1 | 5.85 | 1.35–25.32 | 0.018 | 0.77 | 80 (61–91) | 68 (64–72) | 9 (6–13) | 98 (97–100) |
Age-adjusted hsTnT cut-off value# | 6.59 | 1.93–22.44 | 0.003 | |||||
Additional impact of RV dysfunction on echocardiography | ||||||||
sPESI ≥1 | 5.07 | 1.16–22.22 | 0.031 | 0.79 | 61 (41–78) | 84 (81–87) | 12 (8–20) | 98 (97–99) |
Age-adjusted hsTnT cut-off value# | 4.62 | 1.31–16.29 | 0.017 | |||||
RV dysfunction on echocardiography | 2.33 | 0.92–5.96 | 0.076 | |||||
Subanalysis of 403 patients with sPESI ≥1 | ||||||||
Age-adjusted hsTnT cut-off value# | 5.40 | 1.58–18.47 | 0.007 | 0.66 | 87 (68–96) | 45 (40–50) | 8 (6–13) | 98 (95–99) |
Additional impact of RV dysfunction on echocardiography | ||||||||
Age-adjusted hsTnT cut-off value# | 3.70 | 1.04–13.15 | 0.043 | 0.71 | 67 (45–83) | 72 (67–76) | 12 (8–20) | 97 (95–99) |
RV dysfunction on echocardiography | 2.50 | 0.93–6.77 | 0.071 |
OR: odds ratio; CI: confidence interval; PPV: positive predictive value; NPV: negative predictive value; sPESI: simplified Pulmonary Embolism Severity Index; hsTnT: high-sensitivity troponin T; RV: right ventricular. #: the age-adjusted hsTnT cut-off value was defined as hsTnT levels ≥14 pg·mL−1 in young (age <75 years) patients and hsTnT levels ≥45 pg·mL−1 in elderly (age ≥75 years) patients.