Demographic and clinical features of patients treated with wedge resection and radiofrequency ablation (RFA)
| Wedge resection | RFA | Correlation | |
| Age years | 70 (56–83) | 76 (60–88) | t=−3.60; p=0.041# |
| Sex M/F n | 46/13 | 45/17 | Chi-squared=0.23; p=0.635¶ |
| Baseline performance status+ | 90 (80–100) | 80 (60–90) | t=7.69; p=0.017# |
| Comorbidities n§ | |||
| Cerebrovascular disease | 3 | 5 | |
| Congestive heart failure | 6 | 11 | |
| Coronary artery diseaseƒ | 15 | 19 | |
| Chronic obstructive pulmonary disease | 37 | 32 | |
| Dementia | 2 | 3 | |
| Diabetes mellitus | 9 | 15 | |
| Hepatic disease | 7 | 8 | |
| Hypertension | 17 | 11 | |
| Peripheral arterial disease | 3 | 9 | |
| Renal disease | 6 | 11 | |
| Ulcer disease | 4 | 3 | |
| Other | 5 | 4 | |
| Adult Comorbidity Evaluation 27 score | |||
| 0 | |||
| 1 | 28 | ||
| 2 | 16 | 20 | |
| 3 | 15 | 42 | |
| 1–2 versus 3 | 42 versus 15 | 20 versus 42 | Chi-squared=20.4; p<0.001¶ |
| FEV1 % predicted | 47 (40–56) | 49.5 (27–111) | t=−2.55; p<0.001# |
| FVC % predicted | 57 (39–56) | 59 (35–101) | t=−2.36; p<0.001# |
| BMI kg·m−2 | 24 (20–30) | 26 (20–30) | t =−1.51; p= 0.242# |
| TNM stage n## | Chi-squared=1.38; p=0.241¶ | ||
| T1N0M0 | 16 | 23 | |
| T2N0M0 | 43 | 39 | |
| Tumour size mm | 26 (12–33) | 23 (12–43) | t=−1.362; p=0.175# |
| Histology n | Chi-squared=0.05; p=0.825¶ | ||
| Adenocarcinoma | 35 | 38 | |
| Squamous cell carcinoma | 24 | 24 |
Data are presented as median (range), unless otherwise stated. #: t test; ¶: Chi-squared or Fisher's exact test where appropriate; +: according to Karnofsky scale; §: one patient can be affected by one or more comorbidities; ƒ: coronary artery disease was defined as a positive exercise testing or prior myocardial infarction or prior coronary bypass. ##: for wedge resection, 11 out of 59 T2 cases were due to visceral pleural invasion, all patients underwent lymph node sampling (median number of station 3 (range 2–5), median number of lymph node 9 (range 6–14)), and for RFA, N stage was clinical.