TABLE 1 Anthropometric and clinical variables and acute coronary syndrome (ACS) related risk factors in controls and obstructive sleep apnoea (OSA) patients
ControlOSAp-value
AHI ⩽15 events·h−1AHI >15 events·h−1
Subjects n218213
Age years56.9±12.261.1±10.50.0002
Males178 (82.0)169 (79.7)0.63
Apnoea–hypopnoea index events·h−16.4±4.230.6±14.4<0.00001
Oxygen desaturation index >4% h−19.3±17.924.9±16.9<0.00001
Minimum SaO2 %84.9±10.482.4±7.6<0.00001
Mean SaO2 %93.4±2.092.5±2.00.00003
Time with SaO2 <90% %5.5±13.811.7±18.9<0.00001
Epworth Sleepiness Scale4.3±2.65.5±2.6<0.00001
Hypertensive patients75 (36.6)105 (54.7)0.0004
Body mass index kg·m−226.1±4.228.7±4.2<0.00001
Neck circumference cm40.4±3.941.0±3.40.14
Diabetes mellitus43 (21.1)51 (26.7)0.23
Dyslipidaemia95 (46.3)93 (51.8)0.32
First episode of ACS165 (85.9)134 (77.5)0.049
Cardiomyopathy36 (17.6)47 (24.9)0.10
Stroke5 (2.5)13 (6.8)0.07
Current or former smoker145 (71.1)118 (61.1)0.047
Smoker
 No59 (29.0)75 (38.9)
 Yes98 (48.0)79 (40.9)
 Former smoker47 (23.0)39 (20.2)0.11
Total tobacco exposure pack-years22.7±23.518.6±22.10.09
Alcohol51 (27.3)43 (23.0)0.40
Diuretics29 (14.3)44 (23.9)0.02
Anticoagulants9 (4.5)11 (6.0)0.65
Antiacids35 (17.3)51 (27.7)0.02
Hypolipidemics49 (24.1)68 (37.0)0.009
β-blockers41 (20.4)42 (23.0)0.63
Calcium antagonists9 (4.4)27 (14.8)0.0009
Antiplatelet28 (13.9)46 (25.0)0.008
Insulin9 (4.4)16 (8.7)0.13
Oral antidiabetics32 (15.8)37 (20.3)0.30
  • Data are presented as mean±sd or n (%), unless otherwise stated. SaO2: arterial oxygen saturation. Mann–Whitney and Chi-squared tests were used to assess the differences in the means or proportions between groups. Statistically significant p-values are shown in bold.