Maternal α-tocopherol μg·mL−1 | ||
Adjusted OR (95% CI)#,¶ | p-value | |
Postal questionnaire+ | ||
Ever wheezed | 0.71 (0.43–1.19) | 0.198 |
Wheeze in past year | 0.74 (0.39–1.41) | 0.365 |
Wheezed in absence of a cold in past year | 0.76 (0.35–1.64) | 0.477 |
Doctor confirmed asthma | 0.64 (0.35–1.17) | 0.148 |
Asthma and wheeze in past year | 0.80 (0.37–1.71) | 0.563 |
Asthma medication in past year | 0.58 (0.31–1.10) | 0.096 |
Augmented follow-up§ | ||
Asthma medication in past year | 0.52 (0.31–0.87) | 0.013 |
Longitudinalƒ | ||
Wheeze in past year## | 0.80 (0.57–1.12) | 0.194 |
Doctor confirmed asthma¶¶ | 0.79 (0.51–1.22) | 0.284 |
Asthma and wheeze in past year## | 0.76 (0.49–1.18) | 0.219 |
#: adjusted for maternal smoking during pregnancy, maternal atopy, birth order, child’s sex, maternal age at recruitment, Scottish Index of Multiple Deprivation, birth weight, birth crown-heel length, birth head circumference and maternal vitamin D intake; ¶: OR expressed per standard deviation increase in α-tocopherol, adjusted for plasma cholesterol and gestational age when sample taken; +: n=934; §: n=1748; ƒ: 1, 2, 5 and 10 year data; ##: generalised estimating equations; ¶¶: discrete hazards modelling, hazard ratio.