TABLE 1 Characteristics of mothers at recruitment, those responding to the 10-year follow-up questionnaire and those for whom routinely collected healthcare data were available for their child at 10 years of age
All mothers of singleton childPostal questionnaire respondentsAugmented follow-up
Characteristicsp-value#Characteristicsp-value#
Subjects n19249341748
Maternal characteristics
 Median (IQR) age at recruitment years29 (26–33)31 (27–34)<0.00129 (26–33)0.143
 Current smoker at recruitment566 (29.4)190 (20.4)<0.001515 (29.5)0.493
 Median (IQR) SIMD at recruitment8.86 (5.30–16.78)7.65 (5.72–22.21)<0.0018.83 (5.39–16.00)0.341
 Age left full time education18.3 (18.1–18.4)18.6 (18.4–18.9)<0.00118.3 (18.1–18.4)0.939
 Ever wheeze708 (36.8)310 (33.2)0.002630 (36.0)0.840
 Ever asthma316 (16.4)141 (15.1)0.129293 (16.8)0.121
 Atopy689 (35.8)329 (35.4)0.615626 (35.8)0.130
 First pregnancy656 (35.8)313 (35.0)0.455649 (37.1)0.411
 FFQ returned1717 (89.2)909 (97.4)<0.0011595 (91.2)0.679
 Dietary supplements %44.7%45.4%0.50644.4%0.079
 Vitamin D intake μg·day−13.60 (3.50–3.71)3.66 (3.52–3.81)0.3293.65 (3.49–3.71)0.832
 Vitamin E intake mg·day−18.20 (8.10–8.39)8.14 (7.89–8.39)0.4598.20 (8.01–8.39)0.965
 Plasma α-tocopherol mg·L−19.68 (9.54–9.82)9.68 (9.48–9.89)0.8829.66 (9.51–9.81)0.863
 Vitamin C intake mg·day−1119 (116–122)121 (117–125)0.158119 (116–123)0.280
 Plasma ascorbate μmol·L−161.2 (59.8–62.8)64.0 (61.9–66.1)0.00161.0 (59.3–62.5)0.800
 β-carotene intake mg·day−11.84 (1.77–1.90)1.89 (1.81–1.98)0.0791.83 (1.76–1.90)0.124
 Plasma β-carotene mg·L−10.254 (0.246–0.263)0.273 (0.261–0.285)<0.0010.256 (0.247–0.264)0.253
Child’s characteristics
 Female956 (49.7)486 (52.1)0.038873 (50.0)0.613
 Median (IQR) birth weight g3460 (3090–3797)3520 (3060–3770)0.0083460 (2940–3785)0.502
  • Data are presented as n (%) or geometric mean (95% CI), unless otherwise stated. IQR: interquartile range; SIMD: Scottish Index of Multiple Deprivation; FFQ: Food Frequency Questionnaire. #: p-values for those with data versus remaining cohort members, using Chi-squared, Mann–Whitney or t-tests; : data for age left full time education are presented as mean (95% CI).