TABLE 1

Characteristics of idiopathic pulmonary arterial hypertension (iPAH) patients and controls

iPAHControls
Patients1010
Age years54.9±3.141.9±2.1
Sex male/female (ratio)3/7 (0.43)4/6 (0.67)
NYHA functional class
 Class I2NA
 Class II5NA
 Class III3NA
6MWD m465±20NA
Mean PAP mmHg48.8±3.5NA
Cardiac index Lmin−1·m−22.9±0.2NA
PVRI Wood unit·m−28.3±0.9NA
PCWP mmHg8.4±0.7NA
Specific PAH therapy
 ERA8NA
 PDE5i6NA
 Prostanoids2NA
 No treatment0NA
  • Data are presented as n or mean±sem, unless otherwise stated. NYHA: New York Heart Association; 6MWD: 6-min walking distance; PAP: pulmonary arterial pressure; PVRI: pulmonary vascular resistance index; PCWP: pulmonary capillary wedge pressure; ERA: endothelin receptor antagonists; PDE5i: phophodiesterase 5 inhibitors; NA: not applicable.