TABLE 4

Multivariate analysis and odds ratio estimates for distinguishing clinical features of tuberous sclerosis complex (TSC) and sporadic lymphangioleiomyomatosis (LAM) and sporadic LAM

TSC–LAMSporadic LAMp-value
Multivariate analysis
 Patients n73319
 Age at diagnosis years38.0±10.741.5±9.20.017
 Age at first symptoms years34.2±10.338.0±9.50.007
 Angiomyolipoma89360.003
 Lymphangioleiomyoma1541<0.001
Odds ratio estimates
 Angiomyolipomas2.54 (1.372–4.701)0.017
 Lymphangioleiomyomas0.237 (0.101–0.554)0.003
 Age0.962 (0.931–0.993)<0.001