TABLE 1 Characteristics of healthy and asthmatic study children
HealthyAsthmaticp-value
Children n6650
Age years7.8 (7.7–7.9)8.4 (7.8–9.4)<0.0001
Sex female/male n26/4017/330.55
Birth weight g3310 (3060–3560)3300 (2970–3550)0.54
Birth weight z-score−0.07 (−0.50–0.43)−0.19 (−0.81–0.50)0.58
Maternal tobacco smoke during pregnancy9# (15)9 (18)0.64
Current body mass index z-score0.02 (−0.41–0.70)0.26 (−0.36–1.39)0.14
Current caretakers tobacco smoke17 (27)22+ (45)0.06
Caretaker until 2 years of age<0.0001
 Family1330
 Nanny219
 Nursery278
Wheezing before 3 years of age25 (38)35 (70)0.001
Family history
 Eczema and/or allergic rhinitis39 (59)NA
 Asthma23 (35)NA
Personal history
 Eczema18 (27)18§ (38)0.25
 Allergic rhinitis2 (3)18 (36)<0.0001
 Food allergy2 (3)12ƒ (26)0.0003
 Respiratory allergyNA32/47## (68)
Current exhaled nitric oxide ppb11 (8.5–14.8)NA
  • Data are presented as median (interquartile range) or n (%) of the total population (N), unless otherwise stated. NA: not available. #: N=61; : N=62; +: N=49; §: N=48; ƒ: N=46; ##: N=47.