Frequencies of cytokine secreting T cells in TB patients during treatment
Antigens | Cytokines | Frequencies(Median[IQR],iSFCs/10e6 PBMC) | P value | |
Baseline | 6 months after treatment | |||
ESAT-6 | IFN-γ-only | 272[66-815] | 62[21-156] | 0.006 |
IL-2-only | 38[11-142] | 30[7-68] | 0.119 | |
Dual IFNγ/IL-2 | 8[0-45] | 20[0-65] | 0.575 | |
CFP-10 | IFN-γ-only | 166[60-286] | 62[9-225] | 0.006 |
IL-2-only | 4[0-132] | 14[4-46] | 0.694 | |
Dual IFNγ/IL-2 | 4[0-14] | 12[0-30] | 0.046 |