TABLE 1 Average Spearman's rank correlation coefficients between the secondary electrospray ionisation-mass spectrometry peak intensities and host-derived parameters of lung inflammation up to 48 h post-exposure
Positive correlationsNegative correlations
m/z 56m/z 70m/z 97m/z 115m/z 121m/z 41m/z 43m/z 44m/z 63m/z 94
G-CSF0.71 ± 0.13*0.73 ± 0.10#0.82 ± 0.02-0.74 ± 0.17*-0.71 ± 0.16*-0.82 ± 0.14-0.71 ± 0.18*
IL-6-0.80 ± 0.18*-0.70 ± 0.14*-0.78 ± 0.16*
KC-0.81 ± 0.05-0.76 ± 0.06-0.84 ± 0.17
MIP-1β0.78 ± 0.01-0.71 ± 0.18*
RANTES0.79 ± 0.25#0.78 ± 0.15#0.81 ± 0.23#0.81 ± 0.16*0.73 ± 0.32*-0.76 ± 0.01
TNF-α-0.72 ± 0.11#
PMNs0.71 ± 0.13#0.74 ± 0.13*0.79 ± 0.04#-0.79 ± 0.18*-0.72 ± 0.27*-0.79 ± 0.19#
WBCs0.74 ± 0.13*0.75 ± 0.09#0.79 ± 0.03-0.77 ± 0.22#-0.79 ± 0.16#
  • Data are presented as mean ± sem. m/z: mass-to-charge ratio; G-CSF: granulocyte-colony stimulating factor; IL-6: interleukin-6; KC: keratinocyte-derived chemokine; MIP-1β: macrophage inflammatory protein-1β; TNF: tumour necrosis factor; PMNs: polymorphonuclear neutrophils; WBCs: white blood cells. *: p < 0.05; #: p < 0.001; : p < 0.0001.