Unadjusted hazard ratios and 95% confidence intervals for right ventricle ejection fraction (RVEF) and major risk factors in predicting all-cause and cardiovascular mortality
| Variables | All-cause mortality | Cardiovascular mortality | ||
| HR (95% CI) | p-value | HR (95% CI) | p-value | |
| Age >10 years | 1.42 (1.14–1.76) | 0.001 | 1.36 (1.08–1.71) | 0.008 |
| Male | 1.47 (0.79–2.74) | 0.229 | 2.02 (1.03–3.99) | 0.040 |
| BMI >1 kg·m−2 | 0.99 (0.93–1.04) | 0.648 | 1.00 (0.94–1.06) | 0.958 |
| NYHA FC III and IV | 1.51 (0.80–2.88) | 0.206 | 1.46 (0.73–2.92) | 0.287 |
| Clinical evidence of RV failure | 2.43 (1.27–4.66) | 0.008 | 2.39 (1.18–4.84) | 0.016 |
| 6MWT >100 m | 0.60 (0.47–0.76) | <0.001 | 0.60 (0.46–0.78) | <0.001 |
| Right atrial pressure >1 mmHg | 1.05 (0.99–1.11) | 0.133 | 1.07 (1.00–1.13) | 0.050 |
| Mean PAP >1 mmHg | 0.99 (0.97–1.02) | 0.513 | 1.00 (0.98–1.03) | 0.822 |
| Cardiac index >1 L·min−1·m−2 | 0.58 (0.34–0.99) | 0.049 | 0.47 (0.26–0.86) | 0.015 |
| PVR >1 dyn·s·cm−5 | 1.00 (1.00–1.00) | 0.487 | 1.00 (1.00–1.00) | 0.268 |
| TAPSE >1 mm | 0.92 (0.85–1.00) | 0.044 | 0.90 (0.83–0.098) | 0.018 |
| TAPSE median | 0.94 (0.47–1.92) | 0.874 | 1.26 (0.57–2.82) | 0.569 |
| TAPSE ≥20 mm versus <20 mm | 1.13 (0.43–2.920 | 0.810 | 1.17 (0.40–3.400 | 0.770 |
| TAPSV >1 cm·s−1 | 0.91 (0.77–1.07) | 0.264 | 0.88 (0.74–1.06) | 0.183 |
| Severe tricuspid regurgitation | 1.51 (0.21–11.0) | 0.687 | 1.29 (0.18–9.46) | 0.805 |
| RVEF >1% | 0.95 (0.91–0.99 | 0.006 | 0.95 (0.91–0.99) | 0.011 |
| RVEF ≥25% versus <25% | 0.39 (0.20–0.75) | 0.005 | 0.44 (0.22–0.89) | 0.021 |
| NT-proBNP >1000 pg·mL−1 | 1.23 (1.02–1.47) | 0.027 | 1.28 (1.06–1.54) | 0.010 |
| SvO2 >1 mmHg | 0.97 (0.94–1.00) | 0.036 | 0.97 (0.94–1.00) | 0.067 |