Table 5– Studies reporting measurements using the tidal breathing technique of nasal nitric oxide sampling for PCD, healthy and cystic fibrosis patients via a stationary analyser, velum closure measurements are shown if they were performed in the same set of patients
StudyPCDHealthy controlsCystic fibrosis
Subjects nTidal breathing nL·min−1Velum closure nL·min−1Subjects nTidal breathing nL·min−1Velum closure nL·min−1Subjects nTidal breathing nL·min−1Velum closure nL·min−1
Piacentini et al. [22], 200815100.8±17.4206.3±29.1
Piacentini et al. [37], 20104386.3±39.1
Degano et al. [13], 201156.5 (4.5–8)10105 (83.5–127)
Marthin and Nielsen [25], 20115425.8±61.719.0±13.652160.2±64.9272.4±76.01772.9±48.2124.8±103.7
Mateos-Corral et al. [26], 201120Mouth open: 13.3±9.5
Mouth closed: 10.0±6.5
17.9±13.719Mouth open: 281.3±231.9
Mouth closed: 234.7±191.8
366.5±131.732Mouth open: 107.6±58.6
Mouth closed: 85.7±54.6
138.8±84.1
Marthin and Nielsen [17], 20131617.7±16.823.7±22.821145.8±46.7267±74.42181.9±44.0150.3±58.8
Boon et al. [31], 2014388.4 (6–22.2)16.8 (8.1–35.7)49150 (106.5–180)236.4 (198.3–295.8)4654 (36–87)109.5 (75.6–169.6)
  • Data are presented as mean±sd or median (interquartile range), unless otherwise stated. PCD: primary ciliary dyskinesia.