Table 3– Proportion of patients achieving the minimal important difference in various outcomes
SPACEUsual careBetween-group p-value
6 weeks
 CRQ-SR
  Dyspnoea63450.187
  Fatigue47330.085
  Emotion32250.317
  Mastery35290.468
 HADS
  Anxiety33200.242
  Depression28200.195
 ISWT20100.073
 ESWT35170.011
6 months
 CRQ-SR
  Dyspnoea56440.143
  Fatigue46250.010
  Emotion31260.533
  Mastery34230.129
 HADS
  Anxiety28270.847
  Depression25180.286
 ISWT20100.116
 ESWT42160.001

  • Data are presented as % unless otherwise stated. Minimal important differences: self-reported Chronic Respiratory Questionnaire (CRQ-SR) dyspnoea, fatigue, emotion and mastery domains, 0.5 points; Hospital Anxiety and Depression Scale, −1.5 points; incremental shuttle walk test (ISWT), 48 m; endurance shuttle walk test (ESWT), 186 s. SPACE: Self-Management Programme of Activity, Coping and Education.