Table 1– Inhaler devices for currently available inhaled medication in cystic fibrosis
Inhaled drugNebuliserDPIpMDI
Hypertonic saline (7%)+--
Mannitol-+-
Dornase alpha+--
Bronchodilators+++
Inhaled corticosteroids+++
Tobramycin++-
Colistin++-
Aztreonam+--
AmBisome+--
Liposomal amikacin+--
Ciprofloxacin-+-
Vancomycin-+-
Clarithromycin-+-
  • AmBisome is manufactured by Gilead Sciences, Uxbridge, UK. DPI: dry powder inhaler; pMDI: pressurised, metered-dose inhaler.