Table 1– Baseline characteristics of the 386 frail elderly stratified by chronic obstructive pulmonary disease (COPD) status after screening
No COPDNew COPDConfirmed COPDFormer COPD
Subjects n236845016
Age years75.1±5.976.5±6.676.1±6.273.8±5.5
Males103 (43.6)40 (47.6)26 (52.0)5 (31.3)
Current smokers15 (6.4)10 (11.9)9 (18.0)3 (18.8)
Former smokers122 (51.7)51 (60.7)31 (62.0)10 (62.5)
Smoking pack-years3.6 (0.0–20.0)18.8 (0.0–31.1)35.0 (16.5–50.0)15.0 (1.3–22.5)
Asthma9 (3.8)14 (16.7)7 (14.0)9 (56.3)
Hypertension179 (75.8)68 (80.9)28 (56.0)10 (62.5)
Diabetes mellitus80 (33.9)31 (36.9)14 (28.0)3 (18.8)
Atrial fibrillation18 (7.6)7 (8.3)7 (14.0)0 (0.0)
Stroke or TIA27 (11.4)6 (7.1)8 (16.0)3 (18.8)
Peripheral artery disease8 (0.8)4 (4.8)2 (4.0)2 (12.5)
Heart failure86 (36.4)36 (42.9)17 (34.0)3 (18.8)
 Systolic heart failure31 (13.1)11 (13.1)4 (8.0)0 (0.0)
 Diastolic heart failure55 (23.3)25 (29.8)13 (26.0)3 (18.8)
MRC dyspnoea score#2 (2–3)3 (2–4)3 (2–4)2 (2–3)
Exercise intolerance2 (0–3)2 (1–3)3 (1–3)1 (0–4)
Wheeze33 (14.0)35 (41.7)27 (54.0)11 (68.8)
Cough42 (17.8)21 (25.0)21 (42.0)6 (37.5)
Allergy+45 (19.1)14 (16.7)12 (24.0)7 (43.8)
Hyperresponsiveness+30 (12.7)23 (27.4)14 (28.0)8 (50.0)
Pre-bronchodilator FEV1 % predicted95.5±16.870.8±13.864.6±17.785.1±15.9
Post-bronchodilator FEV1 % predicted99.0±16.575.9±14.168.7±17.990.2±15.7
  • Data are presented as mean±sd, n (%) or median (interquartile range), unless otherwise stated. No COPD: no diagnosis of COPD and no COPD according to panel; new COPD: no diagnosis of COPD but COPD according to panel; confirmed COPD: diagnosis of COPD and COPD according to panel; former COPD: diagnosis of COPD but no COPD according to panel. TIA: transient ischaemic attack; MRC: Medical Research Council; FEV1: forced expiratory volume in 1 s. #: situations in which the patients are dyspnoeic are scored as 0 (never), 1 (only during strenuous exercise), 2 (walking fast or uphill), 3 (walking with people of same age), 4 (walking flat), 5 (at rest); : reduced exercise tolerance scores ranging from 0 to 4 based on responses to the questions “do you have a reduced exercise tolerance as compared to others of the same age?”, “do you feel more tired than others of the same age?”, “do you feel you need more recovery time after exercise than others of the same age?” and “do you feel your heart is pounding, or feel palpitations or feel agitated during activities such as walking, gardening or housework?”; +: self-reported.