Table 7– Risk factors associated with bronchiolitis obliterans syndrome
Primary graft dysfunction (PGD)
Acute cellular rejection
Lymphocytic bronchiolitis
Humoral rejection (e.g. de novo anti-human leukocyte antigen antibodies)
Gastro-oesophageal reflux and microaspiration
Infection
 Viral
 Bacterial
 Fungal
Persistent neutrophil influx and sequestration (bronchoalveolar lavage neutrophilia)
Autoimmunity (collagen V sensitisation)