Table 1– Factors associated with polypharmacy at discharge

	Univariate analysis		Multivariate analysis
	OR (95% CI)	p-value	OR (95% CI)	p-value
Age by decade years	1.33 (1.03–1.73)	0.03	1.02 (0.99–1.05)	0.22
10% predicted FEV₁	0.81 (0.67–0.99)	0.038	0.73 (0.57–0.93)	0.01
Charlson index	1.21 (1.01–1.44)	0.03	0.92 (0.76–1.13)	0.43
Heart failure	7.52 (2.95–19.20)	0.0002	3.94 (1.36–11.43)	0.01
Coronary artery disease	3.05 (1.26–7.34)	0.01	2.26 (0.80–6.33)	0.12
Hypertension	3.19 (1.90–5.36)	0.0001	1.71 (0.90–3.26)	0.10
Cardiac arrhythmia	3.49 (1.67–7.29)	0.0009	0.81 (0.33–2.08)	0.68
Diabetes	2.30 (1.23–4.29)	0.009	1.81 (0.85–3.87)	0.12
Osteoporosis	3.37 (1.01–11.28)	0.048	1.39 (0.36–5.39)	0.63
Polypharmacy at admission	19.31 (8.94–41.68)	0.0005	13.10 (5.67–30.28)	0.0002

FEV₁: forced expiratory volume in 1 s.