Smoking-related ILD | ILD in a smoker | Other | p-value | |
Subjects | 8 | 13 | 79 | |
Age years | 47.00±5.00 | 54.64±10.93 | 54.98±11.82 | 0.211 |
Males/females/NA | 4/3/1 | 5/8 | 42/34 | 0.520 |
Smoking history | 0.103 | |||
Never | 1 | 6 | 41 | |
Former/current | 7 | 7 | 38 | |
Pack-years | 34.17±29.90 | 17.83±22.69 | 13.73±28.19 | 0.215 |
Clinical history | 0.642 | |||
Cough yes/no/NA | 5/1/2 | 9/4/0 | 61/15/3 | |
Cough duration months | 16.2±11.14 | 31.00±41.53 | 24.80±35.88 | 0.737 |
Dyspnoea yes/no | 8/0 | 13/0 | 72/7 | 0.368 |
Dyspnoea duration months | 20.62±16.31 | 31.08±39.46 | 23.48±33.76 | 0.732 |
Pulmonary function | ||||
FVC % predicted | 81.90±19.09 | 69.38±9.05 | 64.33±20.38 | 0.045 |
FEV1 % predicted | 79.75±18.28 | 77.38±10.94 | 69.90±20.15 | 0.202 |
FEV1/FVC | 74.50±9.93 | 93.50±14.50 | 94.33±17.17 | 0.02 |
TLC % predicted | 91.17±10.98 | 74.92±10.59 | 68.9±16.67 | 0.0039 |
DLCO % predicted | 48.87±13.72 | 46.08±19.28 | 50.39±19.47 | 0.750 |
Data are presented as n or mean±sd, unless otherwise stated. NA: not available; FVC: forced vital capacity; FEV1: forced expiratory volume in 1 s; TLC: total lung capacity; DLCO: diffusing capacity of the lung for carbon monoxide.