Tiotropium (IR) n=4437	Salmeterol (IR) n=4399	RR (95%CI)
All cardiac events	2.65	2.57	1.03 (0.78, 1.36)
- Cardiac arrhythmia	0.54	0.63	0.85 (0.47, 1.53)
- Myocardial infarction	0.67	0.50	1.33 (0.74, 2.41)
- Other ischaemic heart diseases	0.74	0.63	1.18 (0.68, 2.02)
Stroke	0.38	0.42	0.91 (0.45, 1.85)
IR expressed in 100 pt-yrs. MedDRA v14.1.