Table 1– Clinical, radiographic and histopathological features attributed to smoking in patients with idiopathic interstitial pneumonia
Clinical features
 Preserved pulmonary function with decreased gas transfer
HRCT features
 Emphysema
 Centrilobular nodules
 Cysts in areas of ground-glass opacity
Histopathological features
 Emphysema
 Emphysema-like airspace enlargement with fibrosis
 Respiratory bronchiolitis
 DIP-like foci
 Bronchiolocentric stellate scars (± smooth muscle) (simulating healed PLCH)
  • HRCT: high-resolution computed tomography; DIP: desquamative interstitial pneumonia; PLCH: pulmonary Langerhans’ cell histiocytosis.