Clinical features |
Preserved pulmonary function with decreased gas transfer |
HRCT features |
Emphysema |
Centrilobular nodules |
Cysts in areas of ground-glass opacity |
Histopathological features |
Emphysema |
Emphysema-like airspace enlargement with fibrosis |
Respiratory bronchiolitis |
DIP-like foci |
Bronchiolocentric stellate scars (± smooth muscle) (simulating healed PLCH) |
HRCT: high-resolution computed tomography; DIP: desquamative interstitial pneumonia; PLCH: pulmonary Langerhans’ cell histiocytosis.