Table 3– Summary of prospective trials with stereotactic radiotherapy
First author [ref.]Study designPatients nStageMedian age yearsTotal dose GyDose per fraction Gy2-year overall survival %2-year local recurrence
Baumann [58]Prospective57I7545365Not reported
Bral [62]Prospective40I (n=38)73603–452Not reported
Fakiris [63]Prospective70INot reported60–6636295
Fritz [64]Prospective40I743016395
Le [65]Prospective20INot reported15–3016470
Matsuo [66]Prospective101I774848093
Salazar [67]Prospective60INot reported404Not reportedNot reported
Shibamoto [68]Prospective180I7744–5248085
Taremi [69]Prospective108I7348–603–1063Not reported
Timmerman [70]Prospective55I7254373Not reported
Vahdat [71]Prospective20I7542–6039095
Widder [72]Prospective202I76603–87295
Xia [73]Prospective43I (n=25)715057895