Table 4– Characteristics of World Health Organization group 1 and chronic thromboembolic pulmonary hypertension patients according to end-expiratory pulmonary artery wedge pressure (PAWP)
End-expiratory PAWPp-value
≤15 mmHg>15 mmHg
Subjects n4313
Age years56.1±15.558.9±10.30.54
Female %65.169.20.78
BMI kg·m−227.4 (23.5–30.9)31.8 (27.6–35.9)0.015
mPAP mmHg41 (34–49)47 (39–62)0.099
PVR dyn·s·cm−5520 (361–846)706 (396–1089)0.36
Cardiac output L·min−14.84 (4.05–6.55)4.85 (4.15–5.40)0.69
RAP mmHg6 (5–9)10 (8–12)0.0028
End-expiratory PAWP mmHg11 (9–12)17 (16–18)<0.0001
PAWPmrc mmHg8 (6–9)13 (12–15)<0.0001
PAWPee−mrc mmHg3 (2–3)5 (4–6)0.0007
Abnormal right ventricle# %70.877.80.69
Left atrial diameter# mm33 (30–37)38 (34–39)0.097
Obstructive sleep apnoea5 (11.6)4 (30.8)0.10
Hypertension14 (32.6)5 (38.5)0.69
Diabetes5 (11.6)3 (23.1)0.30
Coronary artery disease5 (11.6)3 (23.1)0.30
  • Data are presented as mean±sd, median (interquartile range) or n (%), unless otherwise stated. BMI: body mass index; mPAP: mean pulmonary artery pressure; PVR: pulmonary vascular resistance; RAP: right atrial pressure; PAWPmrc: PAWP as mean across respiratory cycle; PAWPee−mrc: mean difference between end-expiratory PAWP and PAWPmrc. #: results only for those with echocardiogram data (n=24 and n=9 for end-expiratory PAWP ≤15 and >15 mmHg, respectively).