Table 3– Characteristics of precapillary phenotype patients according to end-expiratory pulmonary artery wedge pressure (PAWP)
End-expiratory PAWPp-value
≤15 mmHg>15 mmHg
Subjects n6627
Age years59.3±14.859.4±14.10.98
Female %54.659.30.68
BMI kg·m−226.9 (23.5–32.2)29.4 (25.2–33.3)0.20
mPAP mmHg34.5 (28–47)33 (27–47)0.74
PVR dyn·s·cm−5422 (298–658)296 (203–630)0.033
Cardiac output L·min−14.67 (3.70–5.97)5.33 (4.15–6.27)0.40
RAP mmHg5 (4–7)8 (7–12)<0.0001
End-expiratory PAWP mmHg11 (9–13)17 (16–18)<0.0001
PAWPmrc mmHg8 (6–10)13 (12–14)<0.0001
PAWPee−mrc mmHg3 (2–4)5 (3–6)0.0001
Abnormal right ventricle# %68.652.90.27
Left atrial diameter# mm33 (30–37)34 (30–39)0.32
Obstructive lung disease27 (40.9)12 (44.4)0.75
Restrictive lung disease22 (33.3)7 (25.9)0.48
WHO group 1 PAH20 (30.3)6 (22.2)0.43
CTEPH14 (21.2)4 (14.8)0.48
Obstructive sleep apnoea8 (12.1)5 (18.5)0.42
Hypertension29 (43.9)13 (48.2)0.71
Diabetes12 (18.2)6 (22.2)0.65
Coronary artery disease9 (13.6)8 (29.6)0.070
  • Data are presented as mean±sd, median (interquartile range) or n (%), unless otherwise stated. BMI: body mass index; mPAP: mean pulmonary artery pressure; PVR: pulmonary vascular resistance; RAP: right atrial pressure; PAWPmrc: PAWP as mean across respiratory cycle; PAWPee−mrc: mean difference between end-expiratory PAWP and PAWPmrc; WHO: World Health Organization; PAH: pulmonary arterial hypertension; CTEPH: chronic thromboembolic pulmonary hypertension. #: results only for those with echocardiogram data (n=35 and n=17 for end-expiratory PAWP ≤15 and >15 mmHg, respectively).