Table 6– Most significant genome-wide association results for the overlap of chronic obstructive pulmonary disease and asthma in the meta-analysis of non-Hispanic whites and African–Americans
ChromosomeSNPGene/nearest geneReference alleleOR (95% CI)p-value
14rs6574978GPR65T1.59 (0.29–1.76)1.18×10−7
14rs8004567GPR65A0.61 (-0.68–0.79)1.18×10−7
14rs1441809GPR65A1.58 (0.29–1.761.58×10−7
14rs3759712GALCC0.63 (-0.63–0.80)1.80×10−7
14rs6574977GPR65A0.64 (-0.62–0.81)3.16×10−7
14rs2165570GPR65T0.67 (-0.56–0.82)3.95×10−7
14rs6574980LOC283587T1.60 (0.29–1.78)4.48×10−7
14rs7157094GPR65T0.63 (-0.64–0.81)7.00×10−7
8rs6471581CYP11B2T0.66 (-0.57–0.83)7.74×10−7
8rs4736359CYP11B2T1.51 (0.25–1.67)7.79×10−7
  • SNP: single nucleotide polymorphism.