Table 2– BODE index components for patients with α1-antitrypsin deficiency-related chronic obstructive pulmonary disease by GOLD stage
GOLD stage
IIIIIIIV
SeverityMildModerateSevereVery severe
Subjects n10415783
FEV1 % of predicted97.4±16.861.4±8.140.6±5.927.5±8.5
Body mass index kg·m−221.9±3.222.9±2.724.2±4.322.2±4.2
mMRC dyspnoea score2.1±0.72.3±0.62.6±0.83.5±0.9
6-min walking distance m461.0±109.0503.6±136.3466.6±117.6369.7±124.3
BODE index0.8±0.81.3±1.73.2±1.35.4±1.7

  • Data are presented as mean±sd, unless otherwise stated. BODE: body mass index, airflow obstruction, dyspnoea and exercise capacity; GOLD: Global Initiative for Chronic Obstructive Lung Disease; FEV1: forced expiratory volume in 1 s; mMRC: modified Medical Research Council.