Table 4– Most significant genome-wide association results for the overlap of chronic obstructive pulmonary disease and asthma among non-Hispanic whites
ChromosomeSNPGene/nearest geneMinor alleleMAFβ±sep-value
8rs11779254CSMD1G0.42-0.47±0.101.57×10−6
12rs59569785SOX5C0.17-0.54±0.111.61×10−6
12rs10860172RMSTC0.330.50±0.112.55×10−6
12rs16926459SOX5G0.840.52±0.113.39×10−6
5rs72812713SEMA6AT0.16-0.52±0.114.48×10−6
8rs6997939CSMD1C0.33-0.44±0.104.53×10−6
9rs4298581ZDHHC21C0.07-0.69±0.155.65×10−6
12rs11108963RMSTC0.310.51±0.115.66×10−6
9rs10810196ZDHHC21T0.07-0.71±0.165.75×10−6
9rs112457842ZDHHC21G0.07-0.69±0.155.79×10−6
  • Genes either contain the variant or are located within 500 kb of the variant. SNP: single nucleotide polymorphism; MAF: minor allele frequency.