Table 2– Distinction between temporal patterns of preschool wheeze and recommendations for controller therapy, as issued in the European Respiratory Society 2008 Task Force report [8]
PhenotypeTemporal patternProposed first choice of controller therapy
Episodic viral wheezeWheezing during discrete time periods, often in association with clinical evidence of a viral cold, with absence of wheeze between episodesMontelukast
Multiple-trigger wheezeWheezing that shows discrete exacerbations (as with episodic viral wheeze) but also symptoms between episodesInhaled corticosteroids