Hospital 1 | Hospital 2 | Hospital 3 | Hospital 4 | Hospital 5 | Hospital 6 | Hospital 7 | ANOVA p-value | |
Subjects n | 181 | 41 | 318 | 73 | 99 | 83 | 24 | |
Age years | 70.6±8.9 | 57.6±13.2 | 54.4±18.99 | 45.4±18.6 | 56.5±16.7 | 61.7±13.4 | 67.4±12.1 | 0.0001 |
Male | 85 (47) | 11 (27) | 146 (46) | 22 (30) | 45 (45.4) | 34 (41) | 14 (58) | 0.003 |
Aetiology | 0.0001 | |||||||
Post-infection | 76 (42) | 11 (26.8) | 69 (21.7) | 23 (31.5) | 38 (38.4) | 30 (36.1) | 10 (41.7) | |
Immunodeficiency | 5 (2.8) | 3 (7.3) | 77 (24.2) | 2 (2.7) | 8 (8.1) | 4 (4.8) | 1 (4.2) | |
Other | 17 (9.4) | 11 (26.8) | 61 (19.2) | 22 (30.1) | 15 (15.2) | 21 (25.3) | 6 (25) | |
Idiopathic | 83 (46) | 16 (39) | 111 (35) | 26 (36) | 38 (38) | 28 (34) | 7 (29) | |
Dyspnoea mMRC score | 2.06±1 | 1.73±1 | 1.22±1.21 | 1.22±1.37 | 0.94±0.9 | 1.28±1.1 | 1.46±0.9 | 0.0001 |
Mucopurulent or purulent sputum | 80 (44.2) | 25 (61.5) | 126 (39.6) | 35 (47.9) | 51 (51.2) | 44 (53) | 10 (41.7) | 0.0001 |
Respiratory insufficiency | 43 (24) | 2 (5) | 6 (2) | 5 (7) | 9 (9) | 11 (13) | 5 (21) | 0.0001 |
Lobes affected | 2.56±1.3 | 2.17±1.1 | 2.45±1 | 1.96±0.6 | 2.82±1.1 | 2.87±1.54 | 2.96±1.2 | 0.0001 |
Post-bronchodilator FEV1 % predicted | 60.2±21.5 | 70.8±26.5 | 76.3±26.6 | 67.5±22.1 | 62.3±26.6 | 71.5±26.2 | 54.9±20.5 | 0.0001 |
Chronic colonisation of Pseudomonas aeruginosa | 32 (18) | 15 (36) | 105 (33) | 41 (56) | 30 (30.3) | 21 (25) | 9 (38) | 0.0001 |
Hospitalisations in previous year | 0.29±0.7 | 0.76±1 | 0.98±1.5 | 0.41±0.7 | 0.73±1.4 | 0.66±1 | 1±1.25 | 0.0001 |
Death | 52 (29) | 6 (15) | 51 (16) | 6 (8) | 21 (21) | 12 (14) | 5 (21) | 0.002 |
Data are presented as mean±sd or n (%), unless otherwise stated. n=819. mMRC: Modified Medical Research Council; FEV1: forced expiratory volume in 1 s.