Table 1– Comparative characteristics of the score’s construction and validation cohorts
VariablesInitial cohortConstruction cohortValidation cohort
Subjects n819397422
Age years58.7±17.659.2±17.458.3±17.7
Male356 (43.5)176 (44.3)180 (42.6)
Body mass index kg·m−225.7±4.726.1±4.2825.35±4.98
Dyspnoea mMRC score1.53±1.161.57±1.171.5±1.15
Smoking pack-years5.79±18.15.59±18.235.96±17.9
Appearance of sputum
 Mucous199 (24.5)101 (25.4)98 (23.3)
 Mucopurulent145 (17.7)106 (26.7)39 (9.3)
 Purulent145 (17.7)40 (10.1)105 (25)
Respiratory insufficiency83 (10.1)39 (10.1)44 (10.6)
Number of affected lobes2.52±1.22.45±1.122.59±1.17
Idiopathic bronchiectasis310 (37.9)154 (38.8)156 (37)
FEV1 % predicted68.9±25.968.5±25.668.7 (26.3)
FVC % predicted76.4±20.376±20.176.7±20.6
Chronic colonisation
Pseudomonas aeruginosa260 (31.8)126 (31.8)134 (31.8)
Haemophilus influenzae126 (15.4)62 (15.6)64 (15.2)
 Multiresistant Gram-negative bacteria40 (4.8)18 (4.5)22 (5.2)
Isolation of Staphylococcus aureus42 (5.1)19 (4.8)23 (5.5)
Isolation of fungi178 (21.7)87 (21.9)91 (21.9)
Isolation of atypical mycobacteria23 (2.8)14 (3.5)9 (2.1)
Exacerbations in previous year2.52±2.22.47±2.12.57±2.3
Hospitalisations in previous year0.7±1.20.72±1.30.67±1.2
Chronic treatment
 Systemic antibiotics59 (7.2)28 (7.1)31 (7.35)
 Inhaled antibiotics146 (17.8)75 (18.9)71 (16.8)
 Macrolides110 (13.4)54 (13.6)56 (13.3)
 Oral corticosteroids39 (4.7)18 (4.5)21 (4.9)
Death154 (18.8)79 (19.9)75 (17.8)
  • Data are presented as mean±sd or n (%), unless otherwise stated. mMRC: modified Medical Research Council; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity.