| Subjects | 9219 |
| Age years | 69.5±11.1 |
| Male | 4693 (50.9) |
| Current smokers | 3399 (37.1) |
| Body mass index kg·m−2 | 27.2±6.3 |
| FEV1 % predicted | 60.6±19.9 |
| Severity of airflow limitation by FEV1 % predicted classification | 7480 |
| Mild (≥80%) | 1307 (17.5) |
| Moderate (≥50% and <80%) | 3891 (52.0) |
| Severe (≥30% and <50%) | 1891 (25.3) |
| Very severe (<30%) | 391 (5.2) |
| Number of COPD exacerbations in the past 12 months | 9219 |
| 0 | 5140 (55.8) |
| 1 | 2017 (21.9) |
| ≥2 | 2062 (22.4) |
| Mean rate of exacerbations in the past 12 months per patient per year | 0.89 |
| mMRC dyspnoea score# | 7119 |
| 0 | 1184 (16.6) |
| 1 | 2633 (37.0) |
| 2 | 1952 (27.4) |
| 3 | 1066 (15.0) |
| 4 | 284 (4.0) |
| Comorbidities | |
| Any comorbidity | 7267 (78.8) |
| Cardiovascular disease | 4225 (46.1) |
| Asthma | 2141 (23.4) |
| Cerebrovascular disease | 1504 (16.6) |
| Depression | 1348 (15.2) |
| Cancer | 1314 (14.7) |
| Lung cancer | 308 (3.5) |
| Diabetes | 1244 (13.6) |
| Osteoporosis | 978 (11.0) |
| COPD medication | |
| Any COPD medication | 8053 (87.4) |
| Short-acting β-agonists | 6896 (74.8) |
| Short-acting anticholinergics | 834 (9.0) |
| Tiotropium | 4273 (46.3) |
| ICS | 1228 (13.3) |
| LABA | 476 (5.2) |
| ICS plus LABA combination | 5146 (55.8) |
Data are presented as n, mean±sd or n (%). Percentages are calculated from the number of valid answers to each individual characteristic and, due to missing values, may not necessarily be based on the entire cohort of 9219. FEV1: forced expiratory volume in 1 s; mMRC: modified Medical Research Council; ICS: inhaled corticosteroids; LABA: long-acting β-agonists. #: MRC grades 1–5 were captured, these are equivalent (and have identical wording) to mMRC 0–4, as follows. 0: only breathless with strenuous exercise; 1: breathless when hurrying on the level or up a slight hill; 2: walk slower than people of same age on the level due to breathlessness or stop for breath when walking on level at own pace; 3: stop for breath after walking 100 yards or a few minutes on the level; and 4: too breathless to leave house or breathless when dressing.