First author [ref.] | Year | Study design | Included patients | Age years | Male | Hypotension at admission | Study outcome | Follow-up duration |
Apfaltrer [19] | 2012 | Retrospective | 60 | 65±14.4 | 47 (78) | NA | Death or adverse clinical events§ | 2 months |
Araoz [20] | 2003 | Retrospective | 173 | 60±17 | 106 (61) | NA | Death and adverse clinical events§ | In hospital |
Araoz [21] | 2007 | Retrospective | 1193 | 63±16 | 552 (46) | 64+ | Death | 3 months |
Aviram [22] | 2008 | Retrospective | 145 | 67±19 | 50 (35.5) | NA | All-cause mortality | 1 month |
Baptista [23] | 2013 | Retrospective | 39 | 59.1±19.6 | 18 (46.2) | NA | All-cause mortality | 40 days, 33 months |
Bazeed [24] | 2010 | Retrospective | 48 | 54±22 | 26 (54) | NA | All-cause mortality | In hospital |
Becattini [11] | 2011 | Prospective | 457 | 67±16.2 | 209 (45.7) | 46 | All-cause mortality or clinical deterioration§ | In hospital |
Cai [25]# | 2013 | Retrospective | 1596 | M: 60.8±13.9 NM: 54.5±18.8 | M: 378 (45.3) NM: 336 (44.2) | NA | All-cause mortality | 1 month |
Ceylan [26] | 2011 | Retrospective | 122 | 65±15 | 61 (50) | NA | All-cause mortality | In hospital |
Díaz [27] | 2007 | Retrospective | 89 | 60.2 (27–89) | 35 (39) | NA | Death | 3 months |
Furlan [28] | 2012 | Retrospective | 635 | 58 (18–94) | 304 (48) | NA | Death | 1 month |
Ghaye [29] | 2006 | Retrospective | 82 | 61±15 | 40 (49) | 32+ | All-cause mortality | In hospital |
Gul [30] | 2012 | Prospective | 61 | 62±17 | 23 (37.7) | 0 | Death | 1 month |
Henzler [31] | 2010 | Retrospective | 100 | NA | NA | NA | Death or adverse clinical events§ | 1 month |
Jimenéz [32] | 2013 | Prospective | 848 | 72 (59–80) | 416 (49) | 34 | All-cause mortality | 1 month |
Jeebun [33] | 2010 | Retrospective | 137 | 65±16 (20–90) | 57 (42) | 41 | Death | In hospital |
Kang [34] | 2011 | Retrospective | 260 | 55±18 | 139 (53.5) | 0 | All-cause mortality or adverse outcome§ | 1 month |
Klok [35]¶ | 2010 | Prospective | 113 | 56±17 | 60 (53) | 0 | Death or adverse clinical events§ | 6 weeks |
Kumamaru [36, 37] | 2012 | Retrospective | 200 | 60±16 | 87 (43.5) | NA | PE-related death or clinical deterioration§ | 1 month |
Lu [38] | 2008 | Retrospective | 50 | 60±13 (23–82) | 19 (38) | NA | Death (all-cause and PE-related) | 1 month |
Lu [39] | 2012 | Retrospective | 674 | 58±17 | 302 (44.8) | NA | Death (all-cause and PE-related) | 1 month |
Mansencal [40] | 2005 | Prospective | 46 | 54±16 | 30 (65) | 5 | All-cause mortality | 3 months |
Meyer [41] | 2012 | Prospective | 83 | Male: 61±13 Female: 64±18 | 46 (55) | 0 | All-cause mortality and clinical deterioration | 2 months |
Moroni [42] | 2011 | Retrospective | 226 | 67±17 | 114 (50.4) | 0 | All-cause mortality | 3 months |
Nural [43] | 2009 | Retrospective | 53 | 61 (22–85) | 26 (49) | 20 | All-cause mortality | 1 month |
Ozsu [44] | 2010 | Prospective | 108 | 70 (21–90) | 61 (56) | 0 | All-cause mortality | 1 month |
Ozsu [45] | 2012 | Retrospective | 99 | 67±15 | 34 (34) | 0 | All-cause mortality | 3 months |
Park [46] | 2011 | Retrospective | 56 | 63.5 (52–71) | 28 (50) | 9 | PE-related death or clinical deterioration§ | 1 month |
Quiroz [10] | 2004 | Retrospective | 63 | 58±15 | 27 (43) | 13 | Death or adverse clinical events§ | 1 month |
Schoepf [47] | 2004 | Retrospective | 431 | 59±16 | 192 (45) | 27 | All-cause mortality | 1 month |
Soares [48] | 2013 | Retrospective | 96 | 54±20 | 45 (47) | 2 | All-cause mortality | 3 months |
Stein [49] | 2008 | Retrospective | 157 | 57±17 | 65 (41) | NA | Death (all-cause and PE-related) | In hospital |
van der Bijl [50]¶ | 2011 | Prospective | 113 | 57±16 | 60 (53) | 0 | Death or adverse clinical events§ | 6 weeks |
van der Meer [51] | 2005 | Retrospective | 120 | 59±18 (18–89) | 55 (46) | 0 | Death (all-cause and PE-related) | 3 months |
Venkatesh [52] | 2010 | Retrospective | 125 | 60 (16–94) | 47 (38) | NA | PE-related death | 1 month |
Zondag [53] | 2013 | Post hoc analysis | 496 | 58±17 | 268 (54) | 26 | All-cause mortality | 1 month |
Data are presented as n, mean±sd, mean (range), mean±sd (range) or n (%). M: malignancy; NM: no malignancy; NA: not available; PE: pulmonary embolism. #: data are reported separately for the two study groups; ¶: studies reporting on the same study population; +: systolic blood pressure defined as <100 mmHg; §: adverse clinical events usually included: cardiopulmonary resuscitation, mechanical ventilation, vasopressor therapy for systemic arterial hypotension, thrombolysis, catheter intervention, surgical embolectomy or subsequent admission to the intensive care unit.