Table 3– Frequency of each potential baseline tuberculosis (TB) drug resistance profile among non-multidrug-resistant (non-MDR) TB cases in Moldova# and the number of those that were diagnosed with MDR-TB during treatment
Baseline resistance profileNew casesPreviously treated cases
With each resistance profileDiagnosed with MDR-TB during treatmentWith each resistance profileDiagnosed with MDR-TB during treatment
None detected211476 (3.6)41346 (11.1)
H-mono10711 (10.3)401 (2.5)
R-mono262 (7.7)126 (50.0)
E-mono253 (12.0)30 (0.0)
S-mono25013 (5.2)572 (3.5)
H+E112 (18.2)22 (100.0)
H+S14917 (11.4)6817 (25.0)
R+E20 (0.0)31 (33.3)
R+S101 (10.0)65 (83.3)
E+S61 (16.7)20 (0.0)
H+E+S5015 (30.0)157 (46.7)
R+E+S74 (57.1)44 (100.0)
Any H31745 (14.2)12527 (21.6)
Any R457 (15.6)2617 (65.4)
Any E10125 (24.8)3015 (50.0)
Any S47251 (10.8)15336 (23.5)
Any resistance64869 (10.6)21346 (21.6)
Any 1 drug40829 (7.1)1129 (8.0)
Any 2 drugs17821 (11.8)8125 (30.9)
Any 3 drugs5719 (33.3)1911 (57.9)
Total2762145 (5.2)62692 (14.7)
  • Data are presented as n or n (%). H: isoniazid; R: rifampicin; E: ethambutol; S: streptomycin. Only 43 cases were tested for resistance to pyrazinamide, all tested negative. #: Between January 1, 2007 and December 31, 2010.