Table 1– Prevalence of anti-Helicobacter pylori antibodies and anti-CagA antibodies in an idiopathic pulmonary fibrosis population along with demographic data, functional-test parameters and mortality rates
H. pylori positiveH. pylori negativep-value
Patients n1827
Age years66.8±10.865.7±9.8ns
Males n1619ns
Pulmonary function tests
 FVC % pred53.6±20.370.1±23.10.016
 FEV1 % pred57.4±18.772.1±21.90.026
 FEV1/FVC87.6±11.382.8±7.6ns
 RV % pred75.1±25.987.6±25.6ns
 TLC % pred61.7±16.074.5±19.20.037
DLCO % pred42.0±17.142.2±20.1ns
KCO % pred71.1±23.466.6±20.4ns
ΔFVC %-11-5.30.05
ΔDLCO %-12.6-6ns
Mortality %
 At 6 months61.1280.05
 At 1 year66.637ns
  • Data are expressed as mean±sd, unless otherwise stated. FVC: forced vital capacity; FEV1: forced expiratory volume in 1 s; RV: residual volume; TLC: total lung capacity; DLCO: diffusing capacity of the lung for carbon monoxide; KCO: transfer coefficient of the lung for carbon monoxide; ΔFVC: decline rate expressed as % of FVC; ΔDLCO: decline rate expressed as % of DLCO; ns: not significant.