Age years | 67±10 |
Males | 49 (45) |
Race | |
Caucasian | 87 (80) |
Asian | 17 (16) |
Unknown | 5 |
Smoking history | |
Current smokers | 17 (16) |
Former smokers | 92 (84) |
Pack-years | 46±25 |
Spirometry | |
FEV1 % pred pre-bronchodilator (n=109) | 83±20 |
FEV1 % pred post-bronchodilator (n=97) | 87±19 |
FVC % pred pre-bronchodilator (n=109) | 92±17 |
FVC % pred post-bronchodilator (n=97) | 95±16 |
FEV1/FVC % pre-bronchodilator (n=109) | 70±11 |
FEV1/FVC % post-bronchodilator (n=100) | 70±13 |
DLCO/VA % pred (n=81) | 75±20 |
RV/TLC % (n=73) | 44±10 |
GOLD classification | |
0 | 64 |
1 | 19 |
2 | 20 |
3 | 5 |
4 | 1 |
α1-antitrypsin genotype¶ | |
MM | 104 (97) |
MZ | 3 (3) |
ZZ | 0 (0) |
Data are presented as mean±sd, n (%) or n. FEV1: forced expiratory volume in 1 s; % pred: % predicted; FVC: forced vital capacity; DLCO: diffusing capacity of the lung for carbon monoxide; VA: alveolar volume; RV: residual volume; TLC: total lung capacity; GOLD: Global Initiative for Chronic Obstructive Lung Disease. #: n=109; ¶: two subjects were not genotyped because genomic DNA could not be obtained.