Table 3– Multivariate analysis: variables associated with bilateral infiltrates
OR (95% CI)p-value
Age >50 years versus 18–50 years1.5 (1.07–2.1)0.018
Serotype 32.69 (1.74–4.14)<0.001
Serotype 19A2.75 (1.55–4.88)0.001

  • Odds ratios were adjusted for sex, smoking, alcohol consumption, previous pneumococcal vaccination, period of influenza epidemic, serotypes (1, 3, 12, 19A and 19F) and comorbidities associated with bilateral infiltrates (solid cancer and HIV infection).