Table 3– Correlations between the plasma and sputum markers and demographics, lung function and sputum cell profile
Plasma sRAGEPlasma SP-ASputum MPOSputum NGAL
Age-0.0460.420**0.316**0.379**
BMI-0.064-0.146-0.0010.049
Pack-years-0.260**0.541**0.276*0.319**
FEV1 % pred0.262**-0.428**-0.291*-0.440**
FEV1/FVC %0.117-0.476**-0.232*-0.341**
DLCO % pred0.447**-0.315*-0.315*-0.368**
Sputum neutrophils %-0.302**0.212*0.394**0.434**
Sputum eosinophils %0.0100.344**0.1260.166

  • sRAGE: soluble receptor for advanced glycation end-products; SP-A: surfactant protein A; MPO: myeloperoxidase; NGAL: neutrophil gelatinase-associated lipocalin; BMI: body mass index; FEV1: forced expiratory volume in 1 s; % pred: % predicted; FVC: forced vital capacity; DLCO: diffusing capacity of the lung for carbon monoxide. *: p <0.05; **: p<0.005.