First author [ref.] | Year | Population | Controls | Substrate | Assay | Iron concentration | |
Controls | CF | ||||||
Gifford [27] | 2011 | Adults | None | Expectorated sputum | Inductively coupled plasma mass spectrometry | Not available | Stable 1.11 (0.09–4.01) mg·mL−1 Exacerbation 2.22 (0.77–7.04) mg·mL−1 |
Reid [28] | 2007 | Adult and paediatric | Healthy | Expectorated sputum | Colorimetric | 0 (0–15.8) μmol·L−1 | Pseudomonas aeruginosa infection 34 (2.4–78) μmol·L−1 No P. aeruginosa infection 18 (8–118) μmol·L−1 |
Reid [25] | 2004 | Adult | Healthy | Expectorated sputum | Colorimetric | 0 (0–13.2) μmol·L−1 | Stable 33.3 (0–111.2) μmol·L−1 Exacerbation 44.4 (17.0–128.7) μmol·L−1 |
Stites [24] | 1999 | Adult | Healthy nonsmokers | BALF | Colorimetric | 0±0 μg·dL−1 | 42±11.6 μg·dL−1 |
Stites [26] | 1998 | Adult | Nonsmokers recent URTI | Expectorated sputum | Coulometry | 0±0 ng·mg−1 | 242±47 ng·mg−1 |
Data are presented as median (range) or mean±sd, unless otherwise stated. BALF: bronchoalveolar lavage fluid; URTI: upper respiratory tract infection.