Table 2– Computed tomography findings in patients according to the diffusing capacity of the lung for carbon monoxide (DLCO)
Presence of fibrosisPresence of emphysema
DLCO <45% pred#DLCO ≥45% pred
NoneMildModerateNoneMildModerate
None14 (32)9 (21)8 (18)64 (67)24 (25)4 (4)
Mild3 (7)4 (9)4 (9)1 (1)1 (1)1 (1)
Moderate0 (0)2 (5)0 (0)1 (1)0 (0)0 (0)
  • Data are presented as are n (%). #: n = 44; : n = 96. Computed tomography scan analysis was performed by a blinded radiologist. Mild emphysema was defined by subtle centrilobular emphysema in apical segments of upper lobes; moderate emphysema was defined by a cluster of centrilobular and paraseptal emphysema with a preference for upper lobes; mild fibrosis was defined by focal areas with fine reticular subpleural opacities; moderate fibrosis was defined by a continuous subpleural band of fine reticular opacities restricted to either the upper or lower lobes.