Presence of fibrosis | Presence of emphysema | |||||
DLCO <45% pred# | DLCO ≥45% pred¶ | |||||
None | Mild | Moderate | None | Mild | Moderate | |
None | 14 (32) | 9 (21) | 8 (18) | 64 (67) | 24 (25) | 4 (4) |
Mild | 3 (7) | 4 (9) | 4 (9) | 1 (1) | 1 (1) | 1 (1) |
Moderate | 0 (0) | 2 (5) | 0 (0) | 1 (1) | 0 (0) | 0 (0) |
Data are presented as are n (%). #: n = 44; ¶: n = 96. Computed tomography scan analysis was performed by a blinded radiologist. Mild emphysema was defined by subtle centrilobular emphysema in apical segments of upper lobes; moderate emphysema was defined by a cluster of centrilobular and paraseptal emphysema with a preference for upper lobes; mild fibrosis was defined by focal areas with fine reticular subpleural opacities; moderate fibrosis was defined by a continuous subpleural band of fine reticular opacities restricted to either the upper or lower lobes.