Table 1– Xpert results for pleural fluid and pleural tissue
Diagnostic test results contributing to the diagnosisSubjects nXpert positive in pleural fluidXpert positive in pleural tissue
Tuberculosis334#0
 Positive pleural tissue culture820
 Positive pleural fluid culture000
 Positive pleural fluid smear110
 MTB identified at other site300
 Histopathology with granulomas2420
 Lymphocytic exudate with elevated ADA1810
Alternative diagnosis630#1
 Definite malignancy by pathology or cytology3601
 Pleural tissue culture and histopathology negative for tuberculosis6501
  • MTB: Mycobacterium tuberculosis; ADA: adenosine deaminase. #: sensitivity 13.3% (four out of 30; 95% CI 4–31%) and specificity 100% (61 out of 61; 95% CI 94–100%); : sensitivity 0% (none out of 17; 95% CI 0–20%) and specificity 97.4% (37 out of 38; 95% CI 86–100%).