Table 1– Patient characteristics and bronchoalveolar lavage (BAL) culture findings for the first 12 months following lung transplantation
No bacterial colonisation after transplantationBacterial colonisation after transplantation
Colistin inhalationNo colistin inhalationp-valueColistin inhalationNo colistin inhalationp-value
Patients963223
Inhalation of colistin months24 (13.5–28.5)024 (10–30)0
Age at transplantation years29.8 (19.9–41.6)27.3 (22.1–30.8)0.3831.6 (23.6–34.9)28.2 (24.8–38.1)0.7
Hospitalisation#250.04890.4
Hospitalisation due to infection#150.01770.4
Ambulant antibiotic courses oral or i.v. #0 (0–1.5)1.5 (0.75–3)0.171 (0–1)1 (0–2)0.17
Survival months35.9 (22.6–51.8)39.5 (19–54.2)0.823.3 (17.6–44)42 (19.9–54.2)0.13
BOS-free survival days1002 (572–1215)750 (359–1230)0.5636 (407–1129)598 (368–1119)0.8
No re-colonisation3 (33)00.2
Eradication11 (3)2 (9)0.5
Multiple organisms206 (26)0.01
BAL culture 12 months after transplantation
 No colonisation3000
Pseudomonas aeruginosa532814
Stenotrophomonas maltophilia11
Achromobacter sp.113
Burkholderia sp.1
Serratia sp.1
Klebsiella sp.1
Pseudomonas and Stenotrophomonsa sp.
Pseudomonas and Acromobacter sp.12
Pseudomonas and Klebsiella sp.11
Pseudomonas and Serratia sp.1
Pseudomonas and Burkholderia sp.2
  • Data are presented as n, n (%) or median (interquartile range), unless otherwise stated. Infection was defined as a decline in forced expiratory volume in 1 s, symptoms and positive infectious parameters. BOS: bronchiolitis obliterans syndrome. #: occurring in the first year; : after P. aeruginosa colonisation was proven once, eradication.