Table 2– Crude and adjusted odds ratios of hospitalisation for adrenal insufficiency associated with current, recent, past use and average daily dose of inhaled corticosteroids
CasesControlsCrude ORAdjusted# OR (95% CI)
Subjects n3923920
No use in the past year40.354.3ReferenceReference
Recency of use in the past year
 Current use45.729.82.101.22 (0.85–1.70)
  Low <500 μg per day3.12.61.511.72 (0.83–3.57)
  Intermediate 500–999 μg per day23.018.71.670.92 (0.62–1.35)
  High ≥1000 μg per day19.68.53.241.84 (1.16–2.90)
 Recent use+7.77.51.370.78 (0.46–1.36)
  Low <500 μg per day0.80.91.040.48 (0.09–2.55)
  Intermediate 500–999 μg per day3.64.51.070.67 (0.31–1.38)
  High ≥1000 μg per day3.32.12.770.94 (0.49–2.47)
 Past use§6.48.41.020.74 (0.43–1.30)
  • Data are presented as %, unless otherwise stated. #: adjusted for all factors reported in table 1; : prescription within 90 days before the index date; +: prescription 91–180 days before the index date; §: prescription 181–365 days before the index date.