Table 1– Characteristics of cases of adrenal insufficiency and their matched controls
VariableCasesControls
Subjects n3923920
Age years67.9±18.067.9±18.0
Follow-up years4.3±3.54.3±3.5
Female42.938.0
Hospitalisation for asthma or COPD in the year before the index date1.4±1.70.2±0.6
Visits to respiratory physician in the year before the index date4.3±12.00.7±3.2
Medication use in the year before the index date
 Antibiotics number of prescriptions1.5±3.50.7±1.3
 Respiratory drugs number of prescriptions#11.9±16.96.5±10.2
 OCSs cumulative dosage mg547.4±934.242.5±228.1
 Diabetes drugs25.014.5
 Cardiac drugs74.762.2
 Central nervous system drugs73.753.8
 Osteoporosis drugs33.715.5
 NSAIDs37.032.6
 Narcotics19.44.9
 Antirheumatic drugs14.04.6
 Others90.372.2
  • Data are presented as mean±sd or %, unless otherwise stated. COPD: chronic obstructive pulmonary disease; OCS: oral corticosteroid; NSAIDs: nonsteroidal anti-inflammatory drugs. #: excluding inhaled corticosteroids.