Table 1– Subject characteristics and lung function summarised by obesity and asthma status
Subject characteristicsOANOAOCNOCp-value
Subjects n74249929
Age years11.1±2.811.1±3.012.4±2.211.8±2.90.344
Females47.338.644.469.00.014
Height cm150.5±15.3+143.8±16.1154.0±12.0151.5±15.90.001
Weight kg65.4±24.7,+39.1±13.470.9±18.8¶,+44.1±15.2<0.001
BMI z-score SDS2.1±0.3,+0.2±0.92.1±0.4,+0.1±0.8<0.001
Atopic# yes/no (% yes)27/12 (69.2)§42/8 (84.0),§2/7 (22.2)14/14 (50.0)<0.001
FEV1 % pred96.1±14.196.3±14.094.3±12.797.8±13.10.908
FVC % pred100.5±11.297.4±11.997.4±12.597.0±11.80.581
FEV1/FVC % pred79.2±6.680.7±8.284.1±4.488.0±7.8<0.001
TLC % pred106.8±13.3100.3±10.797.3±9.599.1±9.30.568
FEV1/TLC# %88.5±12.986.5±9.4+96.7±5.399.1±8.00.003
FRC# % pred102.2±23.6116.7±18.793.5±22.0112.0±16.20.046
ERV# % pred86.1±37.1112.3±23.7117.8±24.5121.3±27.20.004
RV# % pred121.4±50.1§120.9±29.6§64.9±36.0101.1±30.70.003
RV/TLC# %24.0±8.0§26.0±7.0§14.0±7.022.0±0.60.005
  • Data are presented as mean±sd or %, unless otherwise stated. OA: obese asthma; NOA: nonobese asthma; OC: obese control; NOC: nonobese control; BMI: body mass index; SDS: standard deviation score; FEV1: forced expiratory volume in 1 s; % pred: % predicted; FVC: forced vital capacity; TLC: total lung capacity; FRC: functional residual capacity; ERV: expiratory reserve volume; RV: residual volume. #: data available on a subset of participants only (OA n=31; NOA n=12; OC n=9; and NOC n=15); : versus NOC; +: versus NOA; §: versus OC; p<0.017 for post hoc analyses. Bold indicates statistical significance.