Controls | OSA patients | p-value | |
Subjects n | 25 | 50 | |
Males % | 76.0 | 88.0 | 0.20 |
BMI kg·m−2 | 25.0 (21.6–27.3) | 24.9 (21.8–27.9) | 0.83 |
Age years | 51.2 (42.7–62.6) | 51.1 (43.8–60.9) | 0.99 |
Clinical systolic BP mmHg | 127 (112–148) | 125 (110–146) | 0.72 |
Clinical diastolic BP mmHg | 85 (76–97) | 80 (69–93) | 0.29 |
AHI events·h−1 | 5.0 (0.0–9.2) | 35.4 (14.9–59.4) | <0.0001 |
RDI events·h−1 | 6.6 (1.0–15.7) | 35.9 (24.1–71.6) | <0.0001 |
Minimal S aO2 % | 90.0 (85.4–92.5) | 84.5 (75.3–90.0) | <0.0001 |
S aO2<90% % TST | 0.00 (0.00–1.00) | 1.00 (0.00–13.2) | <0.0001 |
RAI events·h−1 | 4.9 (1.9–11.0) | 28.0 (12.0–49.1) | <0.0001 |
Plasma glucose mmol·L−1 | 4.7 (4.3–5.3) | 5.1 (4.5–6.1) | 0.03 |
Plasma insulin μUI·mL−1 | 4.2 (2.2–7.11) | 5.48 (2.85–8.57) | 0.11 |
HOMA-IR index | 0.86 (0.50–1.68) | 1.21 (0.63–2.22) | 0.13 |
Total cholesterol mmol·L−1 | 4.77 (3.41–6.17) | 5.68 (4.41–6.62) | 0.004 |
LDL cholesterol mmol·L−1 | 2.76 (1.57–3.92) | 3.55 (2.13–4.36) | 0.003 |
HDL cholesterol mmol·L−1 | 1.52 (0.98–2.40) | 1.52 (1.10–2.13) | 0.94 |
Triglycerides mmol·L−1 | 0.89 (0.52–1.90) | 1.11 (0.68–1.84) | 0.07 |
hsCRP mg·L−1 | 1.00 (0.38–1.74) | 0.95 (0.30–3.30) | 0.61 |
Right carotid IMT mm | 593 (515–653) | 604 (508–805) | 0.44 |
Left carotid IMT mm | 622 (527–780) | 647 (515–872) | 0.32 |
Mean carotid IMT mm | 606 (523–710) | 620 (539–838) | 0.52 |
Overweight/normal BMI % | 48/52 | 46/56 | 0.87 |
Smoking % | 0 | 0 | 1 |
Hypertension % | 4 | 6 | 1 |
Metabolic syndrome % | 0 | 0 | 1 |
Dyslipidemia % | 0 | 20 | 0.03 |
Urinary 11-dTXB2 pg·mg−1 creatinine | 609.0 (265.8–945.3) | 629.3 (266.4–933.1) | 0.56 |
Data are presented as median (10th–90th percentiles), unless otherwise stated. BP: blood pressure; AHI: apnoea/hypopnoea index; RDI: respiratory disturbance index; SaO2: arterial oxygen saturation; TST: total sleep time; RAI: respiratory arousal index; HOMA-IR: homeostasis model assessment of insulin resistance; LDL: low-density lipoprotein; HDL: high-density lipoprotein; hsCRP: high-sensitivity C reactive protein; IMT: intima-media thickness; 11-dTXB2: 11-dehydrothromboxane. Bold indicates statistical significance.