Table 3– Baseline characteristics of controls and obstructive sleep apnoea (OSA) patients free of any known cardiovascular risk factor, matched for age and body mass index (BMI)
ControlsOSA patientsp-value
Subjects n2550
Males %76.088.00.20
BMI kg·m−225.0 (21.6–27.3)24.9 (21.8–27.9)0.83
Age years51.2 (42.7–62.6)51.1 (43.8–60.9)0.99
Clinical systolic BP mmHg127 (112–148)125 (110–146)0.72
Clinical diastolic BP mmHg85 (76–97)80 (69–93)0.29
AHI events·h−15.0 (0.0–9.2)35.4 (14.9–59.4)<0.0001
RDI events·h−16.6 (1.0–15.7)35.9 (24.1–71.6)<0.0001
Minimal S aO2 %90.0 (85.4–92.5)84.5 (75.3–90.0)<0.0001
S aO2<90% % TST0.00 (0.00–1.00)1.00 (0.00–13.2)<0.0001
RAI events·h−14.9 (1.9–11.0)28.0 (12.0–49.1)<0.0001
Plasma glucose mmol·L−14.7 (4.3–5.3)5.1 (4.5–6.1)0.03
Plasma insulin μUI·mL−14.2 (2.2–7.11)5.48 (2.85–8.57)0.11
HOMA-IR index0.86 (0.50–1.68)1.21 (0.63–2.22)0.13
Total cholesterol mmol·L−14.77 (3.41–6.17)5.68 (4.41–6.62)0.004
LDL cholesterol mmol·L−12.76 (1.57–3.92)3.55 (2.13–4.36)0.003
HDL cholesterol mmol·L−11.52 (0.98–2.40)1.52 (1.10–2.13)0.94
Triglycerides mmol·L−10.89 (0.52–1.90)1.11 (0.68–1.84)0.07
hsCRP mg·L−11.00 (0.38–1.74)0.95 (0.30–3.30)0.61
Right carotid IMT mm593 (515–653)604 (508–805)0.44
Left carotid IMT mm622 (527–780)647 (515–872)0.32
Mean carotid IMT mm606 (523–710)620 (539–838)0.52
Overweight/normal BMI %48/5246/560.87
Smoking %001
Hypertension %461
Metabolic syndrome %001
Dyslipidemia %0200.03
Urinary 11-dTXB2 pg·mg−1 creatinine609.0 (265.8–945.3)629.3 (266.4–933.1)0.56
  • Data are presented as median (10th–90th percentiles), unless otherwise stated. BP: blood pressure; AHI: apnoea/hypopnoea index; RDI: respiratory disturbance index; SaO2: arterial oxygen saturation; TST: total sleep time; RAI: respiratory arousal index; HOMA-IR: homeostasis model assessment of insulin resistance; LDL: low-density lipoprotein; HDL: high-density lipoprotein; hsCRP: high-sensitivity C reactive protein; IMT: intima-media thickness; 11-dTXB2: 11-dehydrothromboxane. Bold indicates statistical significance.