Table 1– Baseline characteristics
Mild-to-moderate asthmaSevere asthma
Patients n365283
Age years50 (18–88)51 (17–77)
Female sex5861
BMI kg·m−228 (17–45)27 (18–59)
Age of asthma onset years#39 (0–78)27 (0–70)
Duration of asthma years#5.0 (0.1–78)20 (0.1–76)
Atopy4249
Smoking history#
 Never-smoker5264
 Ex-smoker4033
 Current smoker83
Severe exacerbations in previous year
 <1 per year7328
 1–2 per year1931
 >2 per year841
FEV1 post-bronchodilator % pred97.0 (22–146)84.9 (23.1–133)
ICS dose ≥1000 μg·day−1085
Chronic oral corticosteroid038
Omalizumab07
  • Data are presented as median (range) or %, unless otherwise stated. BMI: body mass index; FEV1: forced expiratory volume in 1 s; % pred: % predicted; ICS: inhaled corticosteroid. #: data derived from questionnaires; not objectively confirmed in 26 patients.