Table 3– Association between endotoxin levels at home and at school, and asthma-suggestive symptoms
Endotoxin exposureAsthma symptoms#Asthma symptoms including sensitisation status#
Atopic asthmaNonatopic asthma
Cases/controls n66/10310/3223/32
In classroom (of participants with home endotoxin measurements)1.06 (0.97–1.17)1.08 (0.96–1.21)1.13 (1.01–1.26)
At home1.03 (0.92–1.16)0.83 (0.62–1.11)0.98 (0.74–1.3)
Endotoxin exposure mutually adjusted
 School1.06 (0.97–1.16)1.12 (1.02–1.23)1.15 (1.02–1.3)
 Home1.02 (0.91–1.15)0.81 (0.62–1.06)0.92 (0.8–1.05)
Endotoxin exposure mutually adjusted and adjusted for additional confounders
 School1.06 (0.98–1.15)0.99 (0.88–1.11)1.11 (0.97–1.27)
 Home1.09 (0.96–1.24)0.87 (0.68–1.11)0.92 (0.76–1.11)
  • Data are presented as OR (95% CI), unless otherwise stated. #: reference categories (controls) were no asthma symptoms, and not sensitised and no asthma symptoms, respectively. An interquartile range increase corresponds with a factor 2.0 endotoxin increase in schools and a factor 3.7 increase in homes. : adjusted for age, sex, building year of home, number people in household, smoking inside home, pets inside bedroom, parental allergies, parental education, school grade and dampness status of the school.