Endotoxin exposure | Asthma symptoms# | Asthma symptoms including sensitisation status# | |
Atopic asthma | Nonatopic asthma | ||
Cases/controls n | 66/103 | 10/32 | 23/32 |
In classroom (of participants with home endotoxin measurements) | 1.06 (0.97–1.17) | 1.08 (0.96–1.21) | 1.13 (1.01–1.26) |
At home | 1.03 (0.92–1.16) | 0.83 (0.62–1.11) | 0.98 (0.74–1.3) |
Endotoxin exposure mutually adjusted | |||
School | 1.06 (0.97–1.16) | 1.12 (1.02–1.23) | 1.15 (1.02–1.3) |
Home | 1.02 (0.91–1.15) | 0.81 (0.62–1.06) | 0.92 (0.8–1.05) |
Endotoxin exposure mutually adjusted and adjusted for additional confounders¶ | |||
School | 1.06 (0.98–1.15) | 0.99 (0.88–1.11) | 1.11 (0.97–1.27) |
Home | 1.09 (0.96–1.24) | 0.87 (0.68–1.11) | 0.92 (0.76–1.11) |
Data are presented as OR (95% CI), unless otherwise stated. #: reference categories (controls) were no asthma symptoms, and not sensitised and no asthma symptoms, respectively. An interquartile range increase corresponds with a factor 2.0 endotoxin increase in schools and a factor 3.7 increase in homes. ¶: adjusted for age, sex, building year of home, number people in household, smoking inside home, pets inside bedroom, parental allergies, parental education, school grade and dampness status of the school.