Never nGOR | Former nGOR | p-value# | New nGOR | p-value# | Persistent nGOR | p-value# | |
Subjects n | 1298 | 139 | 201 | 123 | |||
Age at baseline years | 33.5±7.2 | 34.0±6.8 | 0.45 | 34.1±6.8 | 0.23 | 35.0±7.3 | 0.03 |
Male | 46.1 | 46.0 | 0.99 | 42.8 | 0.39 | 51.2 | 0.28 |
Baseline BMI kg·m−2 | 23.3±3.3 | 23.9±3.3 | 0.07 | 24.0±3.4 | 0.02 | 25.4±4.4 | <0.001 |
Change in BMI kg·m−2 | 1.9±2.2 | 1.5±2.4 | 0.14 | 2.1±2.1 | 0.25 | 2.1±2.7 | 0.38 |
Anti-reflux medication¶ | 6.7 | 13.0 | 0.01 | 41.9 | <0.001 | 57.9 | <0.001 |
Atopy at baseline | 28.8 | 30.0 | 0.78 | 23.9 | 0.18 | 30.2 | 0.75 |
Smoking | 0.05 | 0.87 | 0.22 | ||||
Never | 44.2 | 36.7 | 47.2 | 36.1 | |||
Ex-smoker | 21.6 | 17.3 | 20.6 | 27.9 | |||
Quitter | 12.9 | 17.3 | 12.6 | 11.5 | |||
Smoker | 21.3 | 28.8 | 19.6 | 24.6 |
Data are presented as mean±sd or %, unless otherwise stated. BMI: body mass index. #: calculated with “never nGOR” as a reference group; ¶: any use in the month before follow-up. Bold represents statistical significance.